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Gamma-Glutamyl Transferase ( GGT )

Gamma-Glutamyl Transferase ( GGT )

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GGT, GGTP, and g-GTP are abbreviations of gamma-glutamyl transferase in medical science. It is an enzyme found in the liver and plays a critical role in regulating the gamma-glutamyl cycle. It helps in the degradation of glutathione in the body. GGT also plays a role in xenobiotic detoxification in the body. In addition, it aids in the transmission of amino acids. It is why GGT is found in the bodyโ€™s cell membranes of different tissues. One can discover GGT in the kidneys, bile duct, liver, brain, heart, and other body parts. Since GGT is primarily present in the liver, its quantity should not be high in the bloodstream. 

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Gamma-Glutamyl Transferase (GGT)

Frequently asked questions

A GGT test will measure the amount of gamma-glutamyl in the bloodstream. Abbreviated as GGPT/GGT, gamma-glutamyl is important for several bodily functions. It is an enzyme usually found in the liver and some other parts of the body. When the liver gets damaged, the GGT levels become abnormal. One can say that the GGT test also measures the effectiveness of oneโ€™s liver or bile duct.

If you are suffering from liver disease, you need a GGT test to determine the extent of the damage. People undergoing treatment for liver disease/damage require a GGT test at frequent intervals. With GGT test reports, one can measure the effectiveness of the treatment for liver disease. One needs a GGT test after showing symptoms of liver disease like excessive weakness, vomiting, and abdomen pain.

Any symptom that is related to liver disease demands a GGT test. You will also need a GGT test after the ALP test results are abnormal. Some common symptoms in the body that indicate you need a GGT test are as follows:

  • Excessive weakness
  • Jaundice symptoms
  • Decreased appetite
  • Pain in the abdomen region
  • Swelling in the abdomen region
  • Nausea
  • Vomiting

A GGT test will indicate the current level of GGT in the bloodstream. It will contain the GGT quantity in units per liter (U/L). The GGT test report will also report whether the GGT levels are normal or abnormal.

The normal range for GGTP level in the body is between 5 U/L and 40 U/L. It is crucial to note that GGTP levels are somewhat higher in men than women. After getting the GGT test result, consult your doctor if the levels are abnormal.

The frequency of the GGT test depends on the severity of the liver disease. Someone suffering from a life-threatening liver disease might require the GGT test every month. People suffering from a genetic liver disorder require a GGT test once every six months.

Some diagnostic centres offer home sample collection facilities for a GGT test. However, you will have to pay a little extra for a GGT test at home. Home sample collection for the GGT test is helpful for critical patients.

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