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Creatine Phosphokinase (CPK)

Creatine Phosphokinase (CPK)

Routine

What is the Creatine Phosphokinase CPK Test?

CPK (creatine phosphokinase) is an enzyme found primarily in the heart, brain, and skeletal muscle. A CPK test is a blood test that measures the amount of CPK in the bloodstream. The test is often used to diagnose and monitor conditions that affect muscle tissue, such as muscular dystrophy, myositis, and heart attacks. There are three types of CPK: CPK-MB, CPK-MM, and CPK-BB. CPK-MB is found primarily in the heart muscle and is often used to diagnose heart attacks. CPK-MM is found primarily in skeletal muscle, and CPK-BB is found primarily in the brain. Depending on which type of CPK is elevated, doctors can determine which type of muscle tissue is damaged. 

The CPK test is typically ordered by a healthcare provider when they suspect that a patient may have muscle damage or disease. Symptoms that may prompt a doctor to order a CPK test include muscle pain, weakness, or swelling. The test may also be ordered for individuals who engage in strenuous physical activity or take medications that can cause muscle damage. 

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Test Details

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Frequently asked questions

A higher CPK level may indicate problems with your brain, heart, or skeletal muscles.

Hyperthyroidism, hypothyroidism, microbial infections, kidney failure, Cushing's syndrome, and autoimmune disorders could lead to high CPK levels despite not directly affecting your brain, muscles, or heart.

If you're taking drugs like cocaine, steroids, statins, fibrates, alcohol, amphotericin B, or some anaesthetics, you must inform your doctor before undergoing this test as they may interfere with the test results.

The creatine phosphokinase test is like any other blood test. It is not typically painful.

Can be done anytime. In case you have other tests in addition along with CPK which require fasting, than the sample can be given in fasting state also.

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