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nts. The most frequent heavy metals include nickel, cobalt, chromium, arsenic, iron, zinc, copper, selenium, silver, antimony, thallium, mercury, aluminium, and lead. Some heavy metals are necessary by the body in trace amounts. These include iron, selenium, copper, molybdenum, and zinc. Other heavy metals, such as aluminium, lead, mercury, and arsenic, are unnecessary and often hazardous.
Heavy metals, such as aluminium, are gained from environmental exposure. Heavy metals are commonly found in manufacturing wastes, paints, solvents, and air, water, and soil contaminants. Aluminium can also be passed from a mother to her baby during pregnancy. Exposure to more heavy metals than the body can detoxify can have various negative consequences. Cancer, neurological illness, and developmental defects are examples of these.
Dose, duration of exposure, and the individual's age and health status are all essential factors in determining a heavy metal's propensity for causing disease. The Aluminium Urine Test is used to determine the amounts of aluminium in urine. It is used to identify heavy metal toxicity and its consequences. The test is sometimes administered as part of the heavy metals panel of tests, which also includes lead, mercury, arsenic, cadmium, and chromium testing.
What is Aluminium, 24 Hrs Urine Test?
This test is used to determine the amount of aluminium in a person's urine. Aluminium, Creatinine, along with Aluminium: Creatinine Ratio values are included in the test results. This test needs 24-hour urine samples.
A 24-hour urine sample helps in the analysis of renal issues. It is often recommended to govern how much aluminium or creatinine is cleared by the kidneys. Protein, hormones, minerals, and other chemical components are also measured.
Who should undergo an Aluminium, 24 Hrs Urine test?
Aluminium levels in the diet range from 5 to 10 milligrams per day. All aluminium eaten is eliminated in the urine. However, long-term exposure can produce excretion problems and increased aluminium toxicity. It can build up in a variety of tissues, including the bones, parathyroid glands, and brain:
- Individuals who operate in mines or the aluminium industry are at significant risk of inheriting aluminium toxicity. Other factors that may contribute to aluminium toxicity include:
- When the dialysis technique fails to remove the aluminium levels.
- Aluminium traces found in dialysis fluid or water are absorbed when taken orally.
In such cases, an aluminium blood test is performed to determine aluminium toxicity. An aluminium blood test is also performed frequently to determine the level of aluminium in the blood of a person suffering from renal failure. The brain, kidneys, system, lungs, thyroid, and liver are the primary locations of aluminium build-up in the body. Aluminium may potentially disrupt heme production.
Aluminium levels have been found in parenteral solutions including calcium, magnesium, and phosphate salts. High aluminium levels in lung tissues can also be caused by cannabis and cigarette usage. In such instances, an individual may have calcium replacement in their bones as a result of the disruption of normal osteoid development and mineralisation.
Other reasons may be High blood pressure, Frequent urinary tract infections, and Kidney stones.
What are the symptoms?
The clinical indications for performing the aluminium urine test are listed below:
- Stomach ache
- Vomiting, diarrhoea, or nauseousness
- Paleness
- Fatigue
- Disturbed mental state
- Mees' lines, or horizontal lines, on the nails
- Miscarriage
- Bones that hurt, change shape, or break
- Speech problems
- Slow growth (in children)
How Aluminium, 24-hour urine test is done?
Before the test, patients are advised to refrain from using antacids and other drugs containing aluminium. High concentrations of iodine and gadolinium are known to affect the results of metal tests. Media containing gadolinium or iodine should not be collected for 96 hours.
For this test, you do not need to prepare in any particular way. Please inform your doctor of all prescription drugs and dietary supplements you may be using. A small number of medications could contain aluminium and affect test reports:
- You will be provided huge containers in which to store your pee as well as a container in which to urinate. Make certain you understand how to use them.
- While you are collecting urine, keep it in a cool place. For example, in a refrigerator or an ice-filled cooler.
- You may be instructed to begin collecting at a specified time.
- Choose 24 hours when you will be at home if feasible to avoid having to transfer your pee.
- Notify your medical practitioner if you are pregnant or suspect you are pregnant.
- Ensure that your physician is aware of all medications (including prescription and over-the-counter), herbs, vitamins, and supplements you are consuming.
The urine containers need to be delivered to the lab as soon as possible after the urine collection is finished. You will be given instructions on how and where to take the urine if you are collecting it at home. Your healthcare physician may request further specialised preparation based on your medical condition.
Aluminium, 24-hour urine test results
Normal Reports:
Aluminium levels in the 24-hour test are normally 10 mcg/24 h (micrograms per 24 hours). If your levels are less than this value, it means your aluminium exposure is within acceptable limits.
Abnormal Reports:
Aluminium accumulation over the normal value (5–10 mg) is poisonous and deadly for the brain and bone.
Renal failure may be indicated when there is a high amount of aluminium because the patients are no longer able to remove aluminium through filtering.
Aluminium blood test findings in users with prosthetic implants containing aluminium indicate positive results with values higher than 10ng/mL.
What are the complications of an Aluminium 24-hour urine collection?
A 24-hour urine collection's accuracy could be impacted by specific factors. These consist of:
- Skipping to save some of your urine
- Exceeding the 24-hour collection window and amassing an excessive amount of pee
- Leaking and losing urine from the specimen container
- Collecting urine without keeping it cool
- Acute anxiety
- vigorous workout
- Several foods, including bananas, citrus fruits, vanilla, coffee, tea, chocolate, and tea
- Depending on the exact health issues you have, there can be additional hazards. Before the collection, be sure to talk to your doctor about any worries.
Pathkind Labs determine accurate results for Aluminium 24-hour urine. We take utmost care to perform the test. The sample cut-off time is 2 pm daily and the report is handled in 3 working days from the time the sample reaches the lab:
- We use Metal-free Jerry Can Available that has no preservatives.
- Urine is collected in a dark-coloured bottle to safeguard it from light.
- We use powder-free gloves or sample collection and keep it properly labelled.